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The hypothesis that the book proposes has been around for quite some time and being aggressively promoted by many researchers and authors on various platforms. As the author rightly says, all great stories need a villain. For over thirty years fat was the villain, now sugar is trying to replace fat in this important social role.
With fat in this role, a very nice-looking logical story was created on how fat drives type 2 diabetes.
Doves, Diplomats and Diabetes - Diabetes Research...
The only problem was that this story was not supported by evidence. Now an equally attractive story is created with sugar, and it is time to examine how well it is supported by evidence.
For example it is not only sugar that induces insulin response, many amino acids also induce it. This well-known phenomenon needs to be incorporated in the theory too. In the entire field of obesity and diabetes, it has been a habit to cherry-pick convenient evidence and the author is faithful to this tradition too. For example, the author asserts that fat in muscle tissue leads to muscle insulin resistance. But data on endurance athletes show that they have high levels of intramuscular fat and still are insulin sensitive.
This is not accounted for by the theory. There is increasing evidence that the central nervous system plays a role in the regulation of energy as well as that of insulin response, but the book pretends as if the central nervous system does not exist.
"How did I live without my iPhone Cord?"
Now about evidence. As I was enjoying reading the book, I received news alerts about a debate on whether sugar induced insulin is the driver of diabetes, published in the journal JAMA Internal Medicine. There were enthusiastic promoters of the story in the debate but an equal number of skeptics who did not find the current evidence convincing enough.
But instead the author paints it as an established truth and guaranteed formula to cure type 2 diabetes.
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Diabetes complications and heart disease scientist treating diabetic leg ulcers with maggots. Steroid indused diabetes Hi I'm confused I have been pre diabetic for as long as I can remember a few years ago I had Bariatric Medicine induced diabetes last year and in November I was told that I had diabetes, I was given metformin after that I tested my Type2 Diabetes consultant diabetes Doctor last Friday.
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New to diabetes Hi. View more posts. Related Posts. Help with pre-diabetes Diabetes Type one diabetic. Evol Med Public Health. Published online Feb 5.
Type-2 Diabetes: A burden of our evolution?
Milind Watve. Author information Article notes Copyright and License information Disclaimer. Corresponding author.
- Milind Watve (Author of Doves, Diplomats, and Diabetes).
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Received Oct 24; Accepted Oct Keywords: developmental plasticity; fetal origins of adulthood disease; predictive adaptive response; factorial design. Open in a separate window.
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Figure 1. Conflict of interest: None declared. The evolution of predictive adaptive responses in human life history. Proc R Soc B ; Nettle D, Bateson M. Adaptive developmental plasticity: what is it, how can we recognize it and when can it evolve? A mathematical model of the evolution of individual differences in developmental plasticity arising through parental bet-hedging.
Skin Disorder Of Diabetes Ii Nhs Type – Opther Diabetes Health
Dev Sci ; 19 — Developmental plasticity: bridging research in evolution and human health. Evol Med Pub Health ; this issue. Snell-Rood EC. An overview of the evolutionary causes and consequences of behavioural plasticity. Animal Behav ; 85 — Developmental constraints in a wild primate. Am Nat ; — Engqvist L, Reinhold K. Methods Ecol Evol ; 7 —